- Oxford Library of Psychology
- [UNTITLED]
- Oxford Library of Psychology
- About the Editors
- Contributors
- Introduction to The Oxford Handbook of Cognitive Neuroscience: Cognitive Neuroscience: Where Are We Now?
- Salience, State, and Expression: The Influence of Specific Aspects of Emotion on Attention and Perception
- Emotion: Generation or Construction?
- The Neuroscience of Emotion Regulation: Basic Mechanisms and Their Role in Development, Aging, and Psychopathology
- The Impact of Emotion on Cognition
- Genetics and Emotion
- Visceromotor Sensation and Control
- Development of Emotion and Social Reasoning in Adolescence
- Self-Knowledge
- Perception of Nonverbal Cues
- Face Recognition
- The Cognitive and Neural Basis of Impression Formation
- Theory of Mind: How Brains Think about Thoughts
- The Pleasures and Pains of Social Interactions: A Social Cognitive Neuroscience Perspective
- The Neural Underpinnings of the Experience of Empathy: Lessons for Psychopathy
- Mirror Neurons and the Perception–Action Link
- The Early Development of the Brain Bases for Social Cognition
- Conflict Monitoring and Cognitive Control
- Hierarchical Cognitive Control and the Functional Organization of the Frontal Cortex
- Thinking
- Decision Neuroscience
- Categorization
- Expectancies and Beliefs: Insights from Cognitive Neuroscience
- Cognitive Neuroscience of Numerical Cognition
- Psychopharmacology of Cognition
- Attention Deficit/Hyperactivity Disorder (ADHD)
- Post-Traumatic Stress Disorder (PTSD)
- Generalized Anxiety Disorder and Social Phobia Considered from a Cognitive Neuroscience Perspective
- The Neurobiology of Obsessive-Compulsive Disorder
- Epilogue to The Oxford Handbook of Cognitive Neuroscience Cognitive Neuroscience: Where Are We Going?
- Index
Abstract and Keywords
That genes influence how we feel and behave is without question. Yet despite decades of research, the mechanisms through which this occurs are only recently coming into focus. This chapter reviews studies that have contributed toward narrowing the gap in knowledge regarding genes and emotional behavior. First, the discussion focuses on Williams syndrome, a genetic “lesional” model, which offers an exceptional framework for understanding the relationship between genes, brain circuits, and atypical socioemotional behavior. The chapter then reviews recent findings for the more common case of mood disorders, for which as for most psychiatry conditions the genetics are complex. The concepts of intermediate phenotypes and imaging genetics will be introduced here as tools to address this question. Finally, evidence at the neurochemical level is presented which suggests that prosocial neuropeptides play a crucial role in the neurobiological chain linking genes and emotion.
Keywords: Williams syndrome, microdeletion syndrome, amygdala, fusiform face area, serotonin, 5-HTTLPR, brain-derived neurotrophic factor (BDNF), monoamine oxidase a (MAO-A)
Lukas Pezawas, Division of Biological Psychiatry, Medical University of Vienna, Vienna, Austria
Andreia Santos, Central Institute of Mental Health, Mannheim, Germany
Andreas Meyer-Lindenberg, Central Institute of Mental Health, Mannheim, Germany
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- Oxford Library of Psychology
- [UNTITLED]
- Oxford Library of Psychology
- About the Editors
- Contributors
- Introduction to The Oxford Handbook of Cognitive Neuroscience: Cognitive Neuroscience: Where Are We Now?
- Salience, State, and Expression: The Influence of Specific Aspects of Emotion on Attention and Perception
- Emotion: Generation or Construction?
- The Neuroscience of Emotion Regulation: Basic Mechanisms and Their Role in Development, Aging, and Psychopathology
- The Impact of Emotion on Cognition
- Genetics and Emotion
- Visceromotor Sensation and Control
- Development of Emotion and Social Reasoning in Adolescence
- Self-Knowledge
- Perception of Nonverbal Cues
- Face Recognition
- The Cognitive and Neural Basis of Impression Formation
- Theory of Mind: How Brains Think about Thoughts
- The Pleasures and Pains of Social Interactions: A Social Cognitive Neuroscience Perspective
- The Neural Underpinnings of the Experience of Empathy: Lessons for Psychopathy
- Mirror Neurons and the Perception–Action Link
- The Early Development of the Brain Bases for Social Cognition
- Conflict Monitoring and Cognitive Control
- Hierarchical Cognitive Control and the Functional Organization of the Frontal Cortex
- Thinking
- Decision Neuroscience
- Categorization
- Expectancies and Beliefs: Insights from Cognitive Neuroscience
- Cognitive Neuroscience of Numerical Cognition
- Psychopharmacology of Cognition
- Attention Deficit/Hyperactivity Disorder (ADHD)
- Post-Traumatic Stress Disorder (PTSD)
- Generalized Anxiety Disorder and Social Phobia Considered from a Cognitive Neuroscience Perspective
- The Neurobiology of Obsessive-Compulsive Disorder
- Epilogue to The Oxford Handbook of Cognitive Neuroscience Cognitive Neuroscience: Where Are We Going?
- Index
