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date: 18 September 2019

Abstract and Keywords

The relationship between personality and mood has been recognized for centuries. This chapter describes two personality traits from the Five-Factor Model of personality, Neuroticism and Extraversion, and discusses the associations between these traits and the onset, maintenance, and treatment of major depressive disorder. The six most commonly described models of the relationship between personality and depression are described, and the consequences of each of the models for the assessment and treatment of depression are discussed. Evidence for shared genetic and neurobiological substrates is reviewed. Finally, this chapter details areas in which future research is needed, not only to examine the relationship between personality and depression further, but also to maximize the efficacy of preventive and therapeutic interventions.

Keywords: Neuroticism, Extraversion, depression, prevention, treatment, genetics, neurobiology

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