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date: 26 January 2021

Abstract and Keywords

The fairly recent recognition of hoarding disorder (HD) as a unique diagnostic entity, rather than a dimension of obsessive-compulsive disorder (OCD), has ignited interest in determining the neurobiological correlates of HD (Mataix-Cols et al., 2010). The authors review and summarize research to date on the neurobiology of HD. First, an overview of the phenomenology of HD is provided. Second, the extant neurobiological research as it relates to animal studies, organic hoarding, and nonorganic hoarding are reviewed. Briefly, neuroimaging studies of HD associate frontal and temporal brain regions with excessive acquisition and a desire to save. Third, the neuropsychology of HD is examined. The available data suggest problems of sustained attention and poor use of memory retrieval strategies in those with HD. Fourth, conclusions and suggestions for future research are offered. Last, descriptions of each brain region implicated in HD are provided throughout the chapter.

Keywords: Neurobiology, hoarding disorder, neuroimaging, neuropsychology, phenomenology, organic hoarding, nonorganic hoarding, frontal and temporal brain regions

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