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date: 19 April 2021

Abstract and Keywords

This chapter focuses on the complementary analytical techniques of linkage and association, which have traditionally been used to locate and identify genes influencing traits of interest. These techniques typically require a direct assay of genotypic variation. As such, the chapter will begin by providing a background to the concepts of DNA and genotyping. Following this, the most common methods used for linkage and association will be reviewed.

Keywords: Linkage, association, genome-wide association study, single-nucleotide polymorphisms, case-control, family-based, identity by decent

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