Show Summary Details

Page of

PRINTED FROM OXFORD HANDBOOKS ONLINE (www.oxfordhandbooks.com). © Oxford University Press, 2018. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Handbooks Online for personal use (for details see Privacy Policy and Legal Notice).

date: 21 August 2019

Abstract and Keywords

In the history of medicine, studies of agraphia and alexia have figured prominently in efforts to understand neural underpinnings of cognition. The central historical figure is Jules Dejerine (1849–1917), whose worked followed pioneering studies on aphasia by Broca and Wernicke. Dejerine identified the left angular gyrus as crucial for reading and writing, and he described syndromes commonly referred to as alexia with agraphia and alexia without agraphia (pure alexia). Models derived from Broca, Wernicke, and Dejerine are based on concepts of specialized cortical centers linked by subcortical nerve fiber pathways. Following his death, Dejerine’s clinical–anatomical formulations were deconstructed by Marie, Head, and Goldstein, only to be resurrected in the second half of the 20th century. Newer varieties of agraphia or alexia were linked to apraxia, impaired body image, spatial misperception, and interhemispheric disconnection; and newer syndromes were identified from information processing approaches focused on error analyses.

Keywords: agraphia, alexia, alexia with agraphia, Dejerine, history of medicine, pure alexia

Access to the complete content on Oxford Handbooks Online requires a subscription or purchase. Public users are able to search the site and view the abstracts and keywords for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can''t find the answer there, please contact us.