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date: 12 July 2020

Abstract and Keywords

This article sets out the context for the problem of insufficient affordable medicines to address health issues in developing countries. It also highlights some of the drivers of recent positive trends. It then detail policies and proposals that are intended to increase access to global medicines (i.e., those with a developed country market) by lowering prices, including differential pricing, compulsory licensing, and donations. Finally, it considers policies that are aimed at encouraging the development of new medicines for neglected diseases (i.e., those prevalent only in lower-income countries) by reducing company-borne costs and risks or by expanding the expected revenue for the manufacturer through increased product demand. In particular, it describes “push” mechanisms that subsidize research inputs and “pull” mechanisms that reward research output.

Keywords: affordable medicine, global medicines, new drugs, neglected diseases, research input

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