Show Summary Details

Page of

PRINTED FROM OXFORD HANDBOOKS ONLINE ( © Oxford University Press, 2018. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Handbooks Online for personal use (for details see Privacy Policy and Legal Notice).

date: 10 April 2021

Abstract and Keywords

Studies using animal models of adolescence have shown lasting consequences of adolescent exposure to alcohol, nicotine, and cannabinoids, including increases in later drug self-administration in some instances, along with alterations in cognitive and socioemotional functioning. In the case of alcohol, some evidence has also emerged for retention of immature, adolescent-typical alcohol sensitivities into adulthood. Neural alterations include relatively long-lasting changes in later neural functioning and gene expression in the neurocircuitry processing rewards, social and emotional stimuli, and cognition. Thus, although at this early stage, other aged exposure groups have not always been included to determine whether adolescence represents an especially vulnerable period, convincing data has nevertheless emerged that repeated exposure to drugs during adolescence often exerts relatively long-lasting alterations in later neurobehavioral function.

Keywords: animal models, adolescent, alcohol, nicotine, cannabinoids, stimulants, substance abuse, rewards, aversions, self-administration

Access to the complete content on Oxford Handbooks Online requires a subscription or purchase. Public users are able to search the site and view the abstracts and keywords for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can''t find the answer there, please contact us.