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date: 24 January 2021

Abstract and Keywords

Comorbidity of physical diseases with mood disorder is substantial and meaningful. Many older people suffer from chronic diseases, which affect mood through their burdensome psychosocial consequences and specific neuropsychiatric sequelae. Medical comorbidity among depressed older persons is also high. Here, through a synergy of behavioural and physiological processes, concurrent mood disorder augments the impact of chronic disease and leads to poor health outcomes. Successful intervention in these patients is limited by a failure to make the diagnosis of depression or by the belief that treatment is unwarranted and likely to be ineffective. Implications for individual practice and the organization of services are discussed with reference to existing literature.

Keywords: mood, depression, physical, medical, comorbidity, neuropsychiatry, demoralization, disability, health, behaviour

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