This article focuses on the challenges inherent in providing healthcare for patients with disfiguring or appearance-related conditions in resource-poor countries across the world. Clinical and research work presented here predominantly related to burns, trauma, and wound healing, so many of the examples come from that area — but the challenges discussed can be extrapolated to cover the provision of care for people with other appearance-related conditions. The article highlights the relative neglect in countries in which rates of injury are high and where need, particularly for physical and psychological rehabilitation, massively outstrips provision. Local priorities are usually to reduce mortality rates rather than to improve the quality of life of survivors of disease and trauma. Distances to healthcare facilities are often considerable, and once patients are physically healed, they return to communities with no facility for follow-up or ongoing psychosocial support.