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date: 17 April 2021

Abstract and Keywords

The illness causes patients to suffer from increasingly severe and widespread dysfunction of the central nervous system leading to disturbances of sleep, sense of smell, autonomic function, cognition, motivation, and mood, as well as decision making and personality. This article concerns the genetics of Parkinson's disease (PD), functional imaging including imaging of pre-symptomatic subjects, and treatment of Parkinsonian diseases including novel treatments, side effects, the placebo effect, potential biases in the evaluation and promotion of therapies, and access to resources as examples of the numerous and varied ethical challenges associated with this neurodegenerative disorder. There are several issues encountered in the management of patients with PD in which ethical considerations may be important.

Keywords: Parkinson's disease, novel treatments, neurodegenerative disorder, ethical challenges, management

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