Abstract and Keywords
This article examines the applications of nanoparticles in medicine. Nanomedicine is a promising field that can make available different nanosystems whose novel, usually size-dependent, physical, chemical and/or biological properties are exploited to combat the disease of interest. One kind of particulate systems represents a vast array of either metallic,semiconductor, polymeric, protein or lipid nanoparticles that can be exploited for diagnosis and treatment of various diseases. This article first provides an overview of general issues related to physicochemical and biological properties of different nanoparticles. It then considers the current problems associated with the use of nanoparticles in medicine and suggests some solutions. It also discusses the interaction of nanoparticles with cells and factors that determine these interactions and concludes with some examples of new approaches for real-time imaging of experimental animals that could be useful, complementary methods for evaluations of effectiveness (or toxicity) of novel nanomaterials andnanomedicines.
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