Studies have linked meaning in life with nearly every other way of measuring the quality and well-being of people’s lives. Despite great empirical strides in meaning in life scholarship, conceptualization on the nature or scope of this important variable seems to be exploding rather than integrating. This chapter discusses the recent convergence among theorists that experiencing the presence of meaning consists of comprehension (making sense of one’s experience), purpose (possessing highly valued goals or missions for one’s life), and significance (perceiving one’s life to be worthwhile and to have value). This chapter also focuses attention on the richness of concepts such as search for meaning, sources of meaning, and orientation to meaning. Finally, this chapter proposes a structural model that unifies these concepts for the first time, portraying how they may be related to each other.