A transactional understanding of problem behaviours recognizes that parents, partners, and other loved ones can often be very relevant to the chain of a client’s self-harm, suicidal behaviour, aggression, and other targets. Because the role of family members is important but often neglected, this chapter focuses primarily on DBT family skills interventions relevant to patient life-threatening behaviours. However, these interventions can readily be adapted for other targets later in treatment. This chapter outlines circumstances under which DBT family interventions might be particularly useful, specific targets to be addressed, rules to establish a treatment target hierarchy, a general protocol for how to conduct a family session, and helpful family session management strategies. DBT family interventions provide an efficient way to augment individual outcomes in DBT and create a more validating family environment that is beneficial for both the client and his or her loved ones.