Abstract and Keywords
Transcranial magnetic stimulation (TMS) is a sophisticated approach for interfering with human memory and reasoning due to its ability to transiently interfere with the functions of the specialized cortical network, especially when applied as repetitive (r)TMS. This article reviews TMS studies dealing with short-term retention, working memory, and with the episodic component of declarative memory. It also considers certain aspects of semantic memory and nonverbal reasoning. Furthermore, it discusses methodological considerations about the experimental designs, which can be used for the investigation of human cognitive functions. This article emphasizes the fact that higher cognitive functions provide an example as to how underlying physiological mechanisms cannot be fully disclosed by investigations based on a single technique. Studies to develop a true multimodal approach are being undertaken. In this light, behavioural interference studies will gain new power in combination with disruptive and correlational methodologies, establishing causality in a more sophisticated manner.
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