Show Summary Details

Page of

PRINTED FROM OXFORD HANDBOOKS ONLINE ( © Oxford University Press, 2018. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Handbooks Online for personal use (for details see Privacy Policy and Legal Notice).

date: 14 November 2019

Abstract and Keywords

Fatigue and sleep disturbance are rampant in today's society and bear significant costs in terms of health-care dollars, productivity, social relationships, and individual quality of life. Fatigue and sleep disturbance often co-occur in relatively healthy populations as well as in several clinical populations. This chapter discusses the psychoneuroimmunological underpinnings of fatigue and sleep disturbance, focusing specifically on the role of pro-inflammatory cytokines as contributors to both fatigue and sleep problems. The chapter provides a basic review of fatigue and sleep, as well as neuro-immune processes underlying these behaviors. Perpetuating factors, treatment approaches, and future research directions are also discussed.

Keywords: fatigue, sleep, sleepiness, sickness behavior, inflammation, HPA

Access to the complete content on Oxford Handbooks Online requires a subscription or purchase. Public users are able to search the site and view the abstracts and keywords for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can''t find the answer there, please contact us.