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date: 17 May 2021

Abstract and Keywords

Aggressivity and impulsivity are traits that are core features of the Cluster B personality disorders. Within these disorders, impulsive aggression leads to a significant amount of morbidity and mortality. This type of behavior is intrinsically linked to violence, suicide, and substance abuse. In this chapter, we will discuss the phenomenology of these traits, the neurobiology of impulsive aggression, and some potential treatment options. We will conclude with some thoughts on the future direction of research in this filed.

Keywords: personality disorders, impulse control disorders, impulsive aggression neurobiology, serotonin, orbitofrontal cortex, TPH2, 5HT2A, treatment

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