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date: 22 September 2019

Abstract and Keywords

Anorexia and bulimia nervosa are complex disorders with dysregulated appetitive behaviors. The underlying causes of disturbed patterns of eating are unknown, but a growing body of research suggests that aberrant functioning of brain or peripheral systems may be responsible. Neuroimaging technologies, such as positron emission tomography (PET) and functional MRI (fMRI), can be used to explore whether there are perturbations of the monoamine systems, the neurocircuitry of gustatory processing in eating disorders, and their relationship to metabolic homeostatic states. Together, PET and fMRI data suggest that individuals with eating disorders have disturbance of taste- and reward-processing regions of the brain, which may contribute to eating disorder symptoms.

Keywords: eating disorder, anorexia nervosa, bulimia nervosa, positron emission tomography, functional magnetic resonance imaging, dopamine, serotonin, anterior insula, orbitofrontal cortex

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