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date: 15 November 2019

Abstract and Keywords

This chapter describes methods of evaluating cognitive change over time using evidence-based practices in the field of clinical neuropsychology. While doing so, a description of cognitive changes during the ‘normal’ ageing process is undertaken, followed by a brief review of cognitive trajectories for a few syndromes associated with abnormal decline. A discussion of the practice of clinical neuropsychology ensues, accompanied by concerns arising when using traditional single time-point assessments. The benefits of and challenges to using serial assessments are also discussed, as well as a basic review of the statistical methods available to identify reliable change over time. The chapter concludes with proposed research directions for the field to better tailor the use of cognitive trajectories to monitor predicted decline in the individual patient.

Keywords: neuropsychology, serial assessment, reliable change, statistics, cognition, dementia

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