- Notes on the Contributors
- Methods in Bioethics
- The Way We Reason Now: Reflective Equilibrium in Bioethics
- Mental Disorder, Moral Agency, and the Self
- ‘Reinventing’ the Rule of Double Effect
- Policy‐Making in Pluralistic Societies
- Tiers Without Tears: the Ethics of a Two‐Tier Health Care System
- Justice and the Elderly
- Organ Transplantation
- For Dignity or Money: Feminists on the Commodification of Women's Reproductive Labour
- The Definition of Death
- The Aging Society and the Expansion of Senility: Biotechnological and Treatment Goals
- Death is a Punch in the Jaw: Life‐Extension and its Discontents
- Precedent Autonomy, Advance Directives, and End‐of‐Life Care
- Physician‐Assisted Death: the State of the Debate
- Abortion Revisited
- Moral Status, Moral Value, and Human Embryos: Implications for Stem Cell Research
- Therapeutic Cloning: Politics and Policy
- Population Genetic Research and Screening: Conceptual and Ethical Issues
- Genetic Interventions and The Ethics of Enhancement of Human Beings
- Pharmacogenomics: Ethical and Regulatory Issues
- Clinical Equipoise: Foundational Requirement or Fundamental Error?
- Research on Cognitively Impaired Adults
- Research in Developing Countries
- Animal Experimentation
- The Implications of Public Health for Bioethics
- Global Health
- Bioethics and Bioterrorism
Abstract and Keywords
The preeminence of informed consent in human subjects protections reflects Western democratic societies' ethical and political commitments to secure each citizen against both coercive and paternalistic influences of other people. Society permits adults extensive personal discretion in choices such as where to live, what to eat, how to dress, and whether to be in research. In short, individuals are afforded extensive discretion in choosing what to do and what is in their own best interests. Informed consent to enroll in research is especially important because research necessarily involves procedures such as randomization and blinding that are done to assure that the project will produce generalizable knowledge.
Jason Karlawish is Associate Professor of Medicine, Fellow of the Center for Clinical Epidemiology and Biostatistics, and Senior Fellow of the Center for Bioethics and the Leonard Davis Institute of Health Economics at the University of Pennsylvania. He is the Associate Director of the Penn Memory Center and the Director of the Alzheimer's Disease Center's Education and Information Transfer Core, University of Pennsylvania. His research focuses on ethical issues in human subjects research and the care of persons with dementia.
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