Show Summary Details

Page of

PRINTED FROM OXFORD HANDBOOKS ONLINE ( © Oxford University Press, 2018. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Handbooks Online for personal use (for details see Privacy Policy and Legal Notice).

date: 02 December 2020

Abstract and Keywords

Aggression is a behavior with evolutionary origins, but in today’s society it’s often both destructive and maladaptive. The fact that aggression has a strong basis in biological factors has long been apparent from case histories of traumatic brain damage. Research over the past several decades has confirmed the involvement of neurotransmitter function and abnormalities in brain structure and function in aggressive behavior. This research has centered around the “serotonin hypothesis” and on dysfunction in prefrontal brain regions. As this literature continues to grow, guided by preclinical research and aided by the application of increasingly sophisticated neuroimaging methodology, a more complex picture has emerged, implicating diverse neurotransmitter and neuropeptide systems (e.g., glutamate, vasopressin, and oxytocin) and neural circuits. As the current pharmacological and therapeutic interventions are effective but imperfect, it is hoped that new insights into the neurobiology of aggression will reveal novel avenues for treatment of this destructive and costly behavior.

Keywords: aggression, personality disorder, borderline, antisocial, impulsivity, neurobiology, neurotransmitter, neuropeptide, neuroimaging

Access to the complete content on Oxford Handbooks Online requires a subscription or purchase. Public users are able to search the site and view the abstracts and keywords for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can''t find the answer there, please contact us.