Abstract and Keywords
This article begins with the question of whether ethics has much to do with normative questions of government policy for the oversight of animal research. It notes that ethics is the normative backbone of such policies—both for animal subjects and human subjects. It finds that numerous parallels have evolved with respect to government-mandated oversight regimes in both the human and the nonhuman animal domains: rules regarding acceptable risk, inappropriate treatment of research subjects, prospective review and approval of proposed research, and institutional oversight committees. Nonetheless, the rules for research on animals depart from those for human research in fundamental ways, and ones that raise moral concerns about whether policies for animal research review are adequate. Policies for human research protections follow and are based on well-articulated moral principles. But the case of animal research has no such clear connection between policies and principles.
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