- The Oxford Handbook of the Auditory Brainstem
- Oxford Handbooks in Neuroscience
- About the Editor
- Contributors
- Introduction and Overview
- Wiring the Cochlea for Sound Perception
- The Diversified Form and Function of Cochlear Afferents
- Efferent Innervation to the Cochlea
- The Cochlear Nuclei: Synaptic Plasticity in Circuits and Synapses in the Ventral Cochlear Nuclei
- In Vitro Studies of Neuromodulation and Plasticity in the Dorsal Cochlear Nucleus
- Molecular and Structural Changes in the Cochlear Nucleus in Response to Hearing Loss
- Age-Related and Noise-Induced Hearing Loss: Central Consequences in the Ventral Cochlear Nucleus
- The Cochlear Nucleus as a Generator of Tinnitus-Related Signals
- Multimodal Inputs to the Cochlear Nucleus and their Role in the Generation of Tinnitus
- Perinatal Development of the Medial Nucleus of the Trapezoid Body
- Extraction of Auditory Information by Modulation of Neuronal Ion Channels
- The Medial Superior Olivary Nucleus: Meeting the Need for Speed
- Lateral Superior Olive: Organization, Development, and Plasticity
- The Superior Paraolivary Nucleus
- Perineuronal Nets in the Superior Olivary Complex: Development, Function, and Plasticity
- The Nuclei of the Lateral Lemniscus
- Axon Trajectories in the Auditory Brainstem
- Neuron Types, Intrinsic Circuits, and Plasticity in the Inferior Colliculus
- Changes in the Inferior Colliculus Associated with Hearing Loss: Noise-Induced Hearing Loss, Age-Related Hearing Loss, Tinnitus and Hyperacusis
- Unifying the Midbrain: The Commissure of the Inferior Colliculus
- Neuromodulatory Feedback to the Inferior Colliculus
- Descending Auditory Pathways and Plasticity
- Aging Processes in the Subcortical Auditory System
- Glial Cells in the Auditory Brainstem
- Deviance Detection and Encoding Acoustic Regularity in the Auditory Midbrain
- Brainstem Encoding of Speech and Music Sounds in Humans
- The Auditory Brainstem Implant: Restoration of Speech Understanding from Electric Stimulation of the Human Cochlear Nucleus
- Index
Abstract and Keywords
The inferior colliculus is an important auditory relay center that undergoes fundamental changes following hearing loss, whether noise induced (NIHL) or age related (ARHL). These changes may contribute to the induction or maintenance of phenomena such as tinnitus (phantom auditory sensations) and hyperacusis (increased sensitivity to sound). Here, we outline changes that can occur in the inferior colliculus following damage to the periphery and/or as a result of the ageing process, both immediate and long-term, and attempt to disentangle which changes relate to either tinnitus or hyperacusis, as opposed to solely hearing loss. Understanding these changes is ultimately important to reversing the underlying pathology and treating these conditions.
Keywords: inferior colliculus, noise-induced hearing loss, age-related hearing loss, presbycusis, tinnitus, hyperacusis
Alan R. Palmer, Medical Research Council Institute of Hearing Research, School of Medicine, The University of Nottingham, UK
Joel I. Berger, Medical Research Council Institute of Hearing Research, School of Medicine, The University of Nottingham, UK
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- The Oxford Handbook of the Auditory Brainstem
- Oxford Handbooks in Neuroscience
- About the Editor
- Contributors
- Introduction and Overview
- Wiring the Cochlea for Sound Perception
- The Diversified Form and Function of Cochlear Afferents
- Efferent Innervation to the Cochlea
- The Cochlear Nuclei: Synaptic Plasticity in Circuits and Synapses in the Ventral Cochlear Nuclei
- In Vitro Studies of Neuromodulation and Plasticity in the Dorsal Cochlear Nucleus
- Molecular and Structural Changes in the Cochlear Nucleus in Response to Hearing Loss
- Age-Related and Noise-Induced Hearing Loss: Central Consequences in the Ventral Cochlear Nucleus
- The Cochlear Nucleus as a Generator of Tinnitus-Related Signals
- Multimodal Inputs to the Cochlear Nucleus and their Role in the Generation of Tinnitus
- Perinatal Development of the Medial Nucleus of the Trapezoid Body
- Extraction of Auditory Information by Modulation of Neuronal Ion Channels
- The Medial Superior Olivary Nucleus: Meeting the Need for Speed
- Lateral Superior Olive: Organization, Development, and Plasticity
- The Superior Paraolivary Nucleus
- Perineuronal Nets in the Superior Olivary Complex: Development, Function, and Plasticity
- The Nuclei of the Lateral Lemniscus
- Axon Trajectories in the Auditory Brainstem
- Neuron Types, Intrinsic Circuits, and Plasticity in the Inferior Colliculus
- Changes in the Inferior Colliculus Associated with Hearing Loss: Noise-Induced Hearing Loss, Age-Related Hearing Loss, Tinnitus and Hyperacusis
- Unifying the Midbrain: The Commissure of the Inferior Colliculus
- Neuromodulatory Feedback to the Inferior Colliculus
- Descending Auditory Pathways and Plasticity
- Aging Processes in the Subcortical Auditory System
- Glial Cells in the Auditory Brainstem
- Deviance Detection and Encoding Acoustic Regularity in the Auditory Midbrain
- Brainstem Encoding of Speech and Music Sounds in Humans
- The Auditory Brainstem Implant: Restoration of Speech Understanding from Electric Stimulation of the Human Cochlear Nucleus
- Index
