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date: 18 September 2020

Abstract and Keywords

This handbook provides an up-to-date, scholarly, and comprehensive review of the spectrum of cognitive disorders in adults. Drawing on contributions from clinicians, clinical researchers, basic and translational scientists, and other experts on their respective topic and leaders in their field, the volume examines current clinical practice and research for adult cognitive disorders ranging from Alzheimer’s disease and vascular dementia to Parkinson’s disease, frontotemporal dementia, chronic traumatic encephalopathy, autism spectrum disorder, and attention-deficit/hyperactivity disorder. Part I deals with cognitive impairment and decline that often occur in the context of normal aging; Part II considers the spectrum of adult cognitive disorders, including the impact of medical and psychiatric disorders on cognitive function, adult neurodevelopmental disorders, and various neurological conditions; and Part III offers unique perspectives and special considerations for the clinician and clinical researcher in adult cognitive disorders, such as the roles of cognitive reserve, genetics, neuropathology, and translational science, as well as ethical and diversity implications. The book also discusses major advances in basic and clinical neuroscience during the past century that have been aimed at reducing the burden associated with adult cognitive disorders, such as those relating to fluid and neuroimaging biomarkers, risk and protective factors of cognitive impairment, and neuropathological and translational research methods.

Keywords: aging, Alzheimer’s disease, cognitive function, cognitive impairment, dementia, neurodevelopment, neurological disorders, neuropsychiatric, neurodegenerative disease

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