- Notes on the Contributors
- List of Abbreviations
- Brain Reading: Decoding Mental States From Brain Activity In Humans
- The Neurobiology of Pleasure and Happiness
- The Neurobiological Basis of Morality
- Development of the Adolescent Brain: Neuroethical Implications for the Understanding of Executive Function and Social Cognition
- Neural Foundations to Conscious and Volitional Control of Emotional Behavior: A Mentalistic Perspective
- Neural Correlates of Deception
- Understanding Disorders of Consciousness
- Functional Magnetic Resonance Imaging, Covert Awareness, and Brain Injury
- Genetic Determinism, Neuronal Determinism, and Determinism Tout Court
- The Rise of Neuroessentialism
- A Neuroscientific Approach to Addiction: Ethical Concerns
- The Neurobiology of Addiction: Implications for Voluntary Control of Behavior
- Neuroethics of Free Will
- Pharmaceutical Cognitive Enhancement
- Cognitive Enhancement
- Chemical Cognitive Enhancement: Is it Unfair, Unjust, Discriminatory, or Cheating for Healthy Adults to Use Smart Drugs?
- Cognitive Enhancement in Courts
- Neuroethics and the Extended Mind
- Does Cognitive Enhancement Fit with the Physiology of Our Cognition?
- Attention Deficit Hyperactivity Disorder: Defining A Spectrum Disorder and Considering Neuroethical Implications
- Why Neuroethicists are Needed
- Intersecting Complexities in Neuroimaging and Neuroethics
- Pediatric Neuroimaging Research
- Ethical Issues in Functional Neurosurgery: Emerging Applications and Controversies
- Non-Invasive Brain Stimulation As A Therapeutic And Investigative Tool: An Ethical Appraisal
- Deep Brain Stimulation For Treatment-Resistant Neuropsychiatric Disorders
- The Ethical Issues of Trials of Neural Grafting in Patients with Neurodegenerative Conditions
- The Ethics Of Nano/Neuro Convergence
- Neurobiological And Neuroethical Perspectives On The Contribution Of Functional Neuroimaging To The Study Of Aging In The Brain
- Clinical Research On Conditions Affecting Cognitive Capacity
- Ethical Concerns And Pitfalls In Neurogenetic Testing
- Neuroethical Issues In Early Detection Of Alzheimer’S Disease
- the neuroethics of cognitive reserve
- Ethical Issues In The Management Of Parkinson’S Disease
- The Other Ethical Challenge of Neurodegenerative Diseases
- Future Scoping: Ethical Issues In Aging And Dementia
- Incidental Findings In Neuroscience Research: A Fundamental Challenge To The Structure Of Bioethics And Health Law
- What Will Be the Limits of Neuroscience-based Mindreading in the Law?
- For The Law, Neuroscience Changes Nothing And Everything
- New Directions In Neuroscience Policy
- Women’s Neuroethics
- Public Representations Of Neurogenetics
- Brain Trust: Neuroscience and national security in the 21st century
- Neuroplasticity, Culture, and Society
- Neuroscience and neuroethics in the 21st century
- Neuroscience and the media: ethical challenges and opportunities
- Ethical issues in Educational Neuroscience: Raising children in a Brave New World
- From The Internationalization To The Globalization Of Neuroethics: Some Perspectives And Challenges
- Global Health Ethics
- Ethical Perspectives: Clinical Drug Trials In Developing Countries
- Learning About Neuroethics Through Health Sciences Online: A Model For Global Dissemination
- Neuroethics And The Lure of Technology
- Subject Index
- Author Index
Abstract and Keywords
This article reviews some of the ethical issues raised by the emergence and use of deep brain stimulation (DBS) as a treatment for neuropsychiatric disorders. Issues include concerns about the capacity of persons with severe mental illness to give authentic informed consent, protecting vulnerable individuals from being exposed to unproven and potentially irreversible therapies, the use of DBS for psychiatric disorders in minors, the necessary organization of the interdisciplinary teams required to deliver these demanding treatments, and the degree and quality of oversight. DBS may be seen as the most recent on a continuum of surgical intervention for psychiatric disease and also represents an adaptation of the first implantable brain-interfacing device (IBID) in clinical use. Consideration of the ethical issues raised by such therapies will protect individuals with neurologic and psychiatric diseases from the abuses of the past.
Debra J.H. Mathews is the Assistant Director for Science Programs at the Johns Hopkins Berman Institute of Bioethics, with a secondary appointment in the Institute of Genetic Medicine, and an Assistant Professor of Pediatrics in the School of Medicine. She has a Ph.D in genetics and a MA in bioethics from Case Western Reserve University.
Peter V. Rabins is Professor of Psychiatry and Behavioral Sciences in the Johns Hopkins Hospital and the Richman Family Professor for Alzheimer’s and Related Diseases. His interests include the effectiveness of current treatment for Alzheimer disease, the development of measures of quality of life in persons with Alzheimer disease and the care of patients with late stage dementia.
Benjamin D. Greenberg is Chief of Adult OCD research at the National Institute of Mental Health (NIMH). He studied psychology at Amherst College, and received a Ph.D in neuroscience from UC San Diego, and an MD from the University of Miami. He was a neurology resident at Columbia University, and completed psychiatry residency at Johns Hopkins Hospital and a fellowship at the NIMH. His primary research for more than a decade has been in psychiatric neurosurgery.
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