The twenty-eight articles in this Handbook represent some of the current thinking in the study of Latin language and literature in the Middle Ages. The insights offered by the collective of authors not only illuminate the field of medieval Latin literature, but shed new light on broader questions of literary history, cultural interaction, world literature, and language in history and society. The contributors illustrate the field's complexities on a wide range of topics through examples and challenges to settled answers of the past. At the same time, they suggest future possibilities for the necessarily provisional and open-ended work essential to the pursuit of medieval Latin studies. The overall approach of the Handbook makes it a resource for students of the ancient world interested in the prolonged after-life of the classical period's cultural complexes, for medieval historians, for scholars of other medieval literary traditions, and for all those interested in delving more deeply into the more-than-millennium that forms the bridge between the ancient Mediterranean world and what we consider modernity.