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Changes in the Inferior Colliculus Associated with Hearing Loss: Noise-Induced Hearing Loss, Age-Related Hearing Loss, Tinnitus and Hyperacusis  

Alan R. Palmer and Joel I. Berger

The inferior colliculus is an important auditory relay center that undergoes fundamental changes following hearing loss, whether noise induced (NIHL) or age related (ARHL). These changes ... More

Chemosensory Transduction in Arthropods  

Monika Stengl

Reception of chemicals via olfaction and gustation are prerequisites to find, distinguish, and recognize food and mates and to avoid dangers. Several receptor gene superfamilies are ... More

Dendritic Targeting and Regulatory RNA Control of Local Neuronal Translation  

Taesun Eom, Ilham A. Muslimov, Anna Iacoangeli, and Henri Tiedge

Online publication date:
Jun 2018
This chapter reviews current developments in the area of translational control in neurons. It focuses on the activity-dependent translational modulation by neuronal regulatory RNAs, ... More

Extraction of Auditory Information by Modulation of Neuronal Ion Channels  

Leonard K. Kaczmarek

All neurons express a subset of over seventy genes encoding potassium channel subunits. These channels have been studied in auditory neurons, particularly in the medial nucleus of the ... More

GABAA Receptor Physiology and Pharmacology  

Martin Wallner, Anne Kerstin Lindemeyer, and Richard W. Olsen

Online publication date:
Mar 2018
GABAA receptors (GABAARs) are the main inhibitory neurotransmitter receptors and mediate rapid synaptic as well as slow extrasynaptic inhibitory neurotransmission. Structurally, GABAARs ... More

Genetic Analysis of Behavior in Drosophila  

Björn Brembs

The main function of brains is to generate adaptive behavior. Far from being the stereotypical, robot-like insect, the fruit fly Drosophila exhibits astounding flexibility and chooses ... More

Large Conductance Potassium Channels in the Nervous System  

Willy Carrasquel-Ursulaez, Yenisleidy Lorenzo, Felipe Echeverria, and Ramon Latorre

Online publication date:
Apr 2018
The Slowpoke (Slo) family of large conductance K+ channels comprises four structurally and functionally related members (Slo1, Slo2.1, Slo2.2, and Slo3). With the exception of Slo3, all ... More

Mechanisms of Axonal Degeneration and Regeneration: Lessons Learned From Invertebrates  

Jiaxing Li and Catherine A. Collins

In the face of acute or chronic axonal damage, neurons and their axons undergo a number of molecular, cellular, and morphological changes. These changes facilitate two types of responses, ... More

Neurotransmitters and Neuropeptides of Invertebrates  

Lynne A. Fieber

This chapter introduces working definitions of neuropeptides and neurotransmitters from the perspective of invertebrate physiological processes. Neuropeptides and neurotransmitters are ... More

Nicotinic Acetylcholine Receptors  

Roger L. Papke

Online publication date:
Mar 2018
Acetylcholine, exquisitely evolved as a neurotransmitter, is made and released by the neurons that take the integrated output of the central nervous system throughout the body. At both ... More