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Age-Related and Noise-Induced Hearing Loss: Central Consequences in the Ventral Cochlear Nucleus  

Ruili Xie, Tessa-Jonne F. Ropp, Michael R. Kasten, and Paul B. Manis

Hearing loss generally occurs in the auditory periphery but leads to changes in the central auditory system. Noise-induced hearing loss (NIHL) and age-related hearing loss (ARHL) affect ... More

Central Nervous System Pain Pathways  

Andrew J. Todd and Fan Wang

Online publication date:
Jul 2018
Nociceptive primary afferents detect stimuli that are normally perceived as painful, and these afferents form synapses in the dorsal horn of the spinal cord and the spinal trigeminal ... More

Changes in the Inferior Colliculus Associated with Hearing Loss: Noise-Induced Hearing Loss, Age-Related Hearing Loss, Tinnitus and Hyperacusis  

Alan R. Palmer and Joel I. Berger

The inferior colliculus is an important auditory relay center that undergoes fundamental changes following hearing loss, whether noise induced (NIHL) or age related (ARHL). These changes ... More

Chemosensory Transduction in Arthropods  

Monika Stengl

Reception of chemicals via olfaction and gustation are prerequisites to find, distinguish, and recognize food and mates and to avoid dangers. Several receptor gene superfamilies are ... More

The Cochlear Nuclei: Synaptic Plasticity in Circuits and Synapses in the Ventral Cochlear Nuclei  

Donata Oertel, Xiao-Jie Cao, and Alberto Recio-Spinoso

Plasticity in neuronal circuits is essential for optimizing connections as animals develop and for adapting to injuries and aging, but it can also distort the processing, as well as ... More

The Cochlear Nucleus as a Generator of Tinnitus-Related Signals  

J.A. Kaltenbach and D.A. Godfrey

Tinnitus most commonly begins with alterations of input from the ear resulting from cochlear trauma or overstimulation of the ear. Because the cochlear nucleus is the first processing ... More

Dendritic Targeting and Regulatory RNA Control of Local Neuronal Translation  

Taesun Eom, Ilham A. Muslimov, Anna Iacoangeli, and Henri Tiedge

Online publication date:
Jun 2018
This chapter reviews current developments in the area of translational control in neurons. It focuses on the activity-dependent translational modulation by neuronal regulatory RNAs, ... More

Descending Auditory Pathways and Plasticity  

Brett R. Schofield and Nichole L. Beebe

Descending auditory pathways originate from multiple levels of the auditory system and use a variety of neurotransmitters, including glutamate, GABA, glycine, acetylcholine, and dopamine. ... More

The Diversified Form and Function of Cochlear Afferents  

Paul Albert Fuchs

Online publication date:
Sep 2018
Cochlear afferents differ in form and function. The great majority are type I, large diameter, myelinated neurons that contact a single inner hair cell to transmit acoustic information. ... More

Dorsal Root Ganglion Neuron Types and Their Functional Specialization  

Edward C. Emery and Patrik Ernfors

Primary sensory neurons of the dorsal root ganglion (DRG) respond and relay sensations that are felt, such as those for touch, pain, temperature, itch, and more. The ability to ... More

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