Show Summary Details

Page of

PRINTED FROM OXFORD HANDBOOKS ONLINE (www.oxfordhandbooks.com). © Oxford University Press, 2018. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Handbooks Online for personal use (for details see Privacy Policy and Legal Notice).

date: 20 April 2019

Abstract and Keywords

The variable amplitude of motor cortex is a striking aspect of the muscle response to transcranial magnetic stimulation. It is easy to produce large motor-evoked potentials (MEPs) in some healthy subjects, while others' cortico-muscular pathways seem barely excitable, even by the strongest available stimuli. MEP amplitude and other measures also vary widely within individuals over time. The factors of these differences among and within individuals are age, gross anatomy of the individuals, genetic factors, and physiological differences associated with behavioural and other traits such as personality, conditions like migraine. The MEP varies over time within individuals at rest under laboratory conditions. These variations can be short term or long term. Differences among neurologically normal individuals have important implications for research using TMS. These differences open doors to new fields of study to neurophysiologists in the treatment and etiology of brain disease.

Keywords: variable amplitude, motor-evoked potential amplitude, transcranial magnetic stimulation, cortico-muscular pathways, neurologically normal individuals, neurophysiologists

Access to the complete content on Oxford Handbooks Online requires a subscription or purchase. Public users are able to search the site and view the abstracts and keywords for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can''t find the answer there, please contact us.